It's rough, but it's got something. Definitely worth having another go at!

Main problems - wobbly linework; proportions of the characters need a lot of work, especially in the more ambitious poses - their limbs just don't seem to work right sometimes. You could push it either to more realistic or to more zany and exaggerated. But I guess you're already improving at this kind of thing. (NB: I can't draw to save my life!)

Stuff I liked:

Script: absolutely fine, if you ask me! Good mix of goofiness and mystery. Why is this perfectly ordinary snakelover walking down a road to nowhere? What IS Circe's deal? I want to know.

That sprite verson of Deno is pretty damn solid.

Colours: I REALLY like your colour palatte here. especially Circe's outfit and the hills and sky in the first couple of pages.

I like your facial expressions, especially Deno smiling at the snake on page 8.

Strong, contrasting character designs. Page 15 shows this off very nicely.
And yeah, that gif of the pendant morphing is smooth.