1 - I think the pilot will cover all of Act 1. People forget not only how short Act 1 actually is, but also how many of the pages in Act 1 specifically are just John 'examining' various objects in his house (posters, objects, fireplace, etc), in an animated format these pages would all become background details, meaning that they would take up exactly 0 seconds of screen time despite being fully included. Act 1 can definitely fit into 11 minutes with minimal changes or cuts with this in mind.
2 - I think it will be good, the team working on it seem to know what they're doing.
3 - I predict that Karkat and Jade will likely feature in a short 'flash forward' section at the end of the pilot, intended to make it clear to the audience that there's a bigger story here and introduce some fan favorite characters, in the hopes of getting people excited enough to get that Season 1 greenlight.
4 - The pilot will be 11 minutes. As for the length of a theoretical Season 1 or full series, that is impossible to really say.
5 - I doubt it.
6 - The content farms will latch onto it if it gets popular enough.
7 - They'll probably think it's pretty interesting, but won't really be sure where the story is actually going.
10? - The animation and voice acting both looked pretty good from my perspective.