I'm interested to see the ways its going to be different. So far an obvious bits are that the kids are all talking out loud rather than needing the gift of gab to communicate outside text, john has a cellphone with a bunny charm, karkat's room seems to be the version from the midnight crew intermission ending rather than hivebent. I kinda hope they're open to getting different with it further and maybe having some june egbert stuff in there? but that one's more of an out there hope.
Not so much in the realm of changes but moreso in the realm of casting and designs I hope if we get to see the alphas in any way we see some poc voice actors cast, and lean more into designs like vintage foods did for roxy in pesterquest.