Calliope is my number 1 and I support her in her transition goals and I cannot believe how much her dysphoria narrative was SLEPT ON in postcanon. I do really relate with Roxy on a lot of things too, so it's easy for me to imagine, idk, Alpha Rose divining her daughter's needs and leaving a lifetime supply full of blue pills next to the Gamecube games.
(Honestly? It kind of works for Rose too--all of Mom Lalonde's pushing overly feminine things on her out of the world's drunkest oversupportiveness.)